25 research outputs found

    Constructing 3-designs from spreads and lines

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    Using the elements of a partial spread of PG(d, q) as points, a class of 3-designs is constructed

    Balanced and strongly balanced Pk-designs

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    AbstractGiven a graph G, a G-decomposition of the complete graph Kv is a set of graphs, all isomorphic to G, whose edge sets partition the edge set of Kv. A G-decomposition of Kv is also called a G-design and the graphs of the partition are said to be the blocks. A G-design is said to be balanced if the number of blocks containing any given vertex of Kv is a constant.In this paper the concept of strongly balanced G-design is introduced and strongly balanced path-designs are studied. Furthermore, we determine the spectrum of those path-designs which are balanced, but not strongly balanced

    Perfect Octagon Quadrangle Systems with an upper C4-system and a large spectrum

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    An octagon quadrangle is the graph consisting of an 8-cycle (x1, x2,..., x8) with two additional chords: the edges {x1, x4} and {x5, x8}. An octagon quadrangle system of order ν and index λ [OQS] is a pair (X,H), where X is a finite set of ν vertices and H is a collection of edge disjoint octagon quadrangles (called blocks) which partition the edge set of λKν defined on X. An octagon quadrangle system Σ=(X,H) of order ν and index λ is said to be upper C4-perfect if the collection of all of the upper 4-cycles contained in the octagon quadrangles form a μ-fold 4-cycle system of order ν; it is said to be upper strongly perfect, if the collection of all of the upper 4-cycles contained in the octagon quadrangles form a μ-fold 4-cycle system of order ν and also the collection of all of the outside 8-cycles contained in the octagon quadrangles form a ρ-fold 8-cycle system of order ν. In this paper, the authors determine the spectrum for these systems, in the case that it is the largest possible

    Severe asthma features in children: a case-control online survey

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    BACKGROUND: Very few studies have explored the distinguishing features of severe asthma in childhood in Europe, and only one study was conducted in Southern Europe. The aim of this study was to provide a detailed characterization of children with severe asthma treated in specialized pediatric asthma centers across Italy. METHODS: We conducted a web-based data collection of family, environmental, clinical and laboratory characteristics of 41 patients aged 6-17 years with severe asthma, defined according to the recent guidelines of the European Respiratory Society and the American Thoracic Society, and 78 age-matched peers with non-severe persistent asthma. The patients have been enrolled from 16 hospital-based pediatric pulmonology and allergy centers in Northern, Central, and Southern Italy. Logistic regression analysis assessed the relationship between patients' characteristics and severe asthma or non-severe persistent asthma. RESULTS: Features independently and significantly associated with severe asthma included lifetime sensitization to food allergens [Odds ratio (OR), 4.73; 95 % Confidence Interval (CI), 1.21-18.53; p = 0.03], lifetime hospitalization for asthma (OR, 3.71; 95 % CI, 1.11-12.33; p = 0.03), emergency-department visits for asthma during the past year (OR = 11.98; 95 % CI, 2.70-53.11; p = 0.001), and symptoms triggered by physical activity (OR = 12.78; 95 % CI, 2.66-61.40; p = 0.001). Quality-of-life score was worse in patients with severe asthma than in subjects with non-severe persistent asthma (5.9 versus 6.6, p = 0.005). Self-perception of wellbeing was compromised in more than 40 % of patients in both groups. Children with severe asthma had lower spirometric z scores than non-severe asthmatic peers (all p < 0.001), although 56 % of them had a normal forced expiratory volume in 1 s. No differences were found between the two groups for parental education, home environment, patients' comorbidities, adherence to therapy, exhaled nitric oxide values, and serum eosinophils and IgE . CONCLUSIONS: As expected, children with severe asthma had more severe clinical course and worse lung function than peers with non-severe persistent asthma. Unlike previous reports, we found greater sensitization to food allergens and similar environmental and personal characteristics in patients with severe asthma compared to those with non-severe persistent asthma. Psychological aspects are compromised in a large number of cases and deserve further investigation

    Severe asthma features in children: A case–control online survey

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    Background: Very few studies have explored the distinguishing features of severe asthma in childhood in Europe, and only one study was conducted in Southern Europe. The aim of this study was to provide a detailed characterization of children with severe asthma treated in specialized pediatric asthma centers across Italy. Methods: We conducted a web-based data collection of family, environmental, clinical and laboratory characteristics of 41 patients aged 6–17 years with severe asthma, defined according to the recent guidelines of the European Respiratory Society and the American Thoracic Society, and 78 age-matched peers with non-severe persistent asthma. The patients have been enrolled from 16 hospital-based pediatric pulmonology and allergy centers in Northern, Central, and Southern Italy. Logistic regression analysis assessed the relationship between patients’ characteristics and severe asthma or non-severe persistent asthma. Results: Features independently and significantly associated with severe asthma included lifetime sensitization to food allergens [Odds ratio (OR), 4.73; 95% Confidence Interval (CI), 1.21–18.53; p = 0.03], lifetime hospitalization for asthma (OR, 3.71; 95% CI, 1.11–12.33; p = 0.03), emergency-department visits for asthma during the past year (OR = 11.98; 95% CI, 2.70–53.11; p = 0.001), and symptoms triggered by physical activity (OR = 12.78; 95% CI, 2.66–61.40; p = 0.001). Quality-of-life score was worse in patients with severe asthma than in subjects with non-severe persistent asthma (5.9 versus 6.6, p = 0.005). Self-perception of wellbeing was compromised in more than 40% of patients in both groups. Children with severe asthma had lower spirometric z scores than non-severe asthmatic peers (all p < 0.001), although 56% of them had a normal forced expiratory volume in 1 s. No differences were found between the two groups for parental education, home environment, patients’ comorbidities, adherence to therapy, exhaled nitric oxide values, and serum eosinophils and IgE. Conclusions: As expected, children with severe asthma had more severe clinical course and worse lung function than peers with non-severe persistent asthma. Unlike previous reports, we found greater sensitization to food allergens and similar environmental and personal characteristics in patients with severe asthma compared to those with non-severe persistent asthma. Psychological aspects are compromised in a large number of cases and deserve further investigation

    Un 3-disegno associato ad una n-fibrazione di PG(2n+1,q)

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    In this paper we prove that a total n-spread of PG(2n+1,q) gives us a new 3-design. Moreover, in the case n=1 we construct some new 2-design using spreads

    Möbius-Kantor configurations in the affine plane of order 7

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